string ImagePath = @"\\My Documents\\sampleimage.jpg";
            string newImagePath = @"\\My Documents\\CompressedImage.jpg";
            Bitmap  ImgTemp;
            ImgTemp = new Bitmap(ImagePath);
            SaveJPGWithCompressionSetting(ImgTemp, newImagePath, 10L);



// Get the desired Codec
private static ImageCodecInfo GetEncoderInfo(String mimeType)
        {
             int j;
            ImageCodecInfo[] encoders;
            encoders = ImageCodecInfo.GetImageEncoders();
            for (j = 0; j < encoders.Length; ++j)
            {
                if (encoders[j].MimeType == mimeType)
                    return encoders[j];
            }
             return null;
}


// Get the desired Encoder and Quality
private void SaveJPGWithCompressionSetting(Image image, string szFileName, long lCompression)
        {
            EncoderParameters eps = new EncoderParameters(1);
            eps.Param[0] = new EncoderParameter(System.Drawing.Imaging.Encoder.Quality, lCompression);
            ImageCodecInfo ici = GetEncoderInfo("image/jpeg");
            image.Save(szFileName, ici, eps);
}